Emerging Tech 2015: Digital genome

Digital genome is one of 10 emerging technologies for 2015 highlighted by the World Economic Forum’s Meta-Council on Emerging Technologies.

While the first sequencing of the 3.2 billion base pairs of DNA that make up the human genome took many years and cost tens of millions of dollars, today your genome can be sequenced and digitized in minutes and at the cost of only a few hundred dollars. The results can be delivered to your laptop on a USB stick and easily shared via the internet. This ability to rapidly and cheaply determine our individual unique genetic make-up promises a revolution in more personalized and effective healthcare.

Many of our most intractable health challenges, from heart disease to cancer, have a genetic component. Indeed, cancer is best described as a disease of the genome. With digitization, doctors will be able to make decisions about a patient’s cancer treatment informed by a tumour’s genetic make-up. This new knowledge is also making precision medicine a reality by enabling the development of highly targeted therapies that offer the potential for improved treatment outcomes, especially for patients battling cancer.

Like all personal information, a person’s digital genome will need to be safeguarded for privacy reasons. Personal genomic profiling has already raised challenges, with regard to how people respond to a clearer understanding of their risk of genetic disease, and how others – such as employers or insurance companies – might want to access and use the information. However, the benefits are likely to outweigh the risks, because individualized treatments and targeted therapies can be developed with the potential to be applied across all the many diseases that are driven or assisted by changes in DNA.

Discover the other emerging technologies on the 2015 list:
Sense and avoid drones
Distributed manufacturing
Additive manufacturing
Computer chips that mimic the human brain
Zero-emission cars
Computers that learn on the job
Precise genetic engineering
A new kind of plastic to cut landfill waste
Next generation robotics

This list was compiled by the Meta-Council on Emerging Technologies, who would like to thank: Justine Cassell, Professor, Human-Computer Interaction, Carnegie Mellon University; Paolo Dario, Director, The BioRobotics Institute, Scuola Superiore Sant’Anna, Pisa; Julia Greer, Professor of Materials Science and Mechanics, California Institute of Technology (Caltech); and Jennifer Lewis, Hansjorg Wyss Professor at the Harvard School of Engineering and Applied Sciences, from theNetwork of Global Agenda Councils; Michael Pellini, President and Chief Executive Officer, Foundation Medicine Inc., from the Technology Pioneers; and William “Red” Whittaker, Professor at Carnegie Mellon University, for their invaluable contributions to the creation of this list.

Image: Empty sample tubes showing their unique ‘2DID numbers’ wait to be filled at Biobank, the worlds largest blood and urine sample freezer near Manchester, northern England, March 18, 2010. REUTERS/Phil Noble