How fish slime could spawn a new kind of antibiotics
Researchers are investigating the microbes found within the mucus coating of fish in search of new antimicrobial and antiviral compounds.
Sandra Loesgen's laboratory is principally interested in target-based drug discovery with a focus on (1) identification of genetically encoded, biologically active natural products from microbial sources, (2) developing new screening techniques for small molecules and proteins that inhibit viral cell entry, and (3) using integrated approaches to elucidate the molecular basis of inhibitor interactions with target viral proteins by means of biophysical and structural studies.